Surname Prothro (Prothro 
) , all around the world, is quite a rare last name. The cognomen Prothro is habitual in the United States, where it is a rare surname, Canada, where it is a very rare surname, and the United Kingdom, where it is an extremely rare surname.
| VARIANT | COUNTRY |
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| Prothro | Brazil, Canada, United Kingdom, United States |
| doc prothro American baseball player, US (b. 1893) |
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| maureen prothro 1919-1998 (b. 1919) |
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| tommy prothro American football player and coach, US (b. 1920) |
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| james warren prothro political scientist (1922-1986), US (b. 1922) |
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| johnnie hines watts prothro American nutritionist (b. 1922) |
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| edwin terry prothro (b. 1919) |
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| gerald d. prothro Business; Former IBM executive |
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| chris prothro college basketball player (2003–2007) Delaware |
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| lindsay o prothro researcher ORCID ID = 0000-0003-3385-8487 |
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| stephanie vanbrakle prothro American softball coach, US (b. 1983) |
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| tyrone prothro American football player, US (b. 1984) |
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| chris prothro US (b. 1982) |
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