Surname Orejuela (Orejuela 
) , around the world, is quite a common last name. The last name Orejuela is habitual in Latin America and the Caribbean, particularly Colombia, where it is quite a common surname, Peru, where it is quite a rare surname, and Panama. Measured by absolute frequency, the name is most common in Colombia, Peru, and Spain. Very seldom, Orejuela is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Orejuela | Philippines, Spain, Colombia, United States, Peru |
| carlos garcés orejuela botanist (b. 1915) |
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jefferson orejuela Ecuadorian association football player, EC (b. 1993) |
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luis manuel orejuela Colombian association football player, CO (b. 1995) |
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| eduardo orejuela Ecuadorian swimmer, EC (b. 1952) |
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| tamara orejuela Ecuadorian swimmer, EC (b. 1953) |
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| jesús orejuela Spanish association football player, ES (b. 1958) |
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| antonio orejuela Spanish footballer, ES (b. 1960) |
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| diego orejuela rodríguez Spanish footballer who played as a midfielder, ES (b. 1962) |
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| carlos orejuela Peruvian footballer, PE (b. 1980) |
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| francisco j orejuela researcher |
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| andrés orejuela |
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