Cognomen Mussio (Mussio 
, موسيو) , in the entire world, is quite a rare family name. The last name Mussio is habitual in Latin America and the Caribbean, particularly Uruguay, where it is quite a common surname, Costa Rica, where it is quite a rare surname, and Trinidad and Tobago. In absolute terms, it most frequently occurs in Argentina, Brazil, and Italy. Very seldom, Mussio is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Mussio | Uruguay, Brazil, Italy, United States, Argentina |
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anthony john king mussio Catholic bishop (1902-1978), US (b. 1902) |
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laurence b. mussio Canadian historian, CA (b. 1964) |
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| magdalo mussio Italian painter, IT (b. 1925) |
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| barbara mussio Italian short track skater, IT (b. 1968) |
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| irene mussio researcher |
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| bruna roniza mussio researcher |
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| giovanni mussio |
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