Cognomen Mphothulo (Mphothulo 
) , worldwide, is a very rare last name. The last name Mphothulo is characteristic of Sub-Saharan Africa, particularly South Africa, where it is a rare surname. Very seldom, Mphothulo is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Mphothulo | South Africa |