Cognomen Macchio (Macchio 
) , in the world, is a rare surname. The surname Macchio is characteristic of Uruguay, where it is a rare surname, the United States, and Italy, where it is a very rare surname. Much less frequently, Macchio is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Macchio | Uruguay, Brazil, Italy, Indonesia, United States |
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karl macchio Austro-Hungarian diplomat (1859-1945), AT (b. 1859) |
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| florian von macchio HR (b. 1802) |
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ralph macchio American comic book editor and writer, US (b. 1938) |
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ralph macchio American actor (born 1961), US (b. 1961) |
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| marina macchio author of Biblioteche oggi |
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| talvin de macchio |
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| julia macchio actress, US (b. 1992) |
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