Cognomen Kleffner (Kleffner 
) , across the world, is quite a rare surname. The surname Kleffner is characteristic of Latvia, where it is a rare surname, Germany, and the United States.
| VARIANT | COUNTRY |
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| Kleffner | Canada, Latvia, United States, United Kingdom, Germany |
| wilhelm joseph kleffner (b. 1873) |
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| josef kleffner German politician (1890-1966), DE (b. 1890) |
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| franz kleffner SS officer, DE (b. 1907) |
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| frank kleffner American pathologist, US (b. 1925) |
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| heike kleffner (b. 1966) |
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| ilka kleffner researcher (ORCID 0000-0003-3207-9684) |
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| klaus kleffner DE (b. 1970) |
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| tinka kleffner (b. 1970) |
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| brett kleffner college basketball player (1987–1987) Idaho |
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| jann k. kleffner (b. 1973) |
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