Cognomen Khlopotina (Khlopotina 
, Хлопотина 
) , throughout the world, is a rare surname. The last name Khlopotina is habitual in Russia, where it is a rare surname, Belarus, and Spain, where it is a very rare surname.
| VARIANT | COUNTRY |
|---|---|
| Khlopotina | Russia, United States, Spain |
| Хлопотина | Belarus, Russia, Ukraine |