Surname Khamphien (Khamphien 
) , in the entire world, is an extremely rare last name. The family name Khamphien is habitual in South-eastern Asia, particularly Thailand, where it is an extremely rare surname. Predominantly, Khamphien is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Khamphien | Laos, United States, Thailand |
Mattern, Vilaysak, Duangmala, Chaiyavong, Vongphakdy, and Souvannalat