Cognomen Isac (Isac 
, Исак 
, איסאק 
) , around the globe, is a common last name. The last name Isac is habitual in Moldova, where it is quite a common surname, Romania, and Kyrgyzstan, where it is quite a rare surname. Measured by absolute frequency, the name is most common in Romania, Mexico, and India. More frequently, Isac is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Isac | Brazil, Mexico, Mozambique, Democratic Republic of the Congo, Romania |
| Исак | Kazakhstan, Russia, Bulgaria, Kyrgyzstan, Armenia |
| איסאק | Israel |
| Исац | Russia |
| antonio isac Engraver; Italian; 1788-1828 (b. 1788) |
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emil isac Romanian diplomat and writer (1886-1954), RO (b. 1886) |
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antoni isac aguilar Spanish politician, ES (b. 1950) |
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| dumitru isac (b. 1914) |
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| george isac Ph.D. (b. 1940) |
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lidia isac Moldavian singer, MD (b. 1993) |
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| doru isac Romanian football manager, RO (b. 1962) |
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| chandrani isac researcher |
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| luminita isac researcher |
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| shajy isac researcher (ORCID 0000-0002-4272-7748) |
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| stelian isac Romanian footballer, RO (b. 1981) |
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| raul isac East Timorese footballer, AU (b. 1988) |
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| jaime sánchez isac ES |
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| raphael isac |
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| jérôme isac |
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