Surname Hofhuis (Hofhuis 
) , worldwide, is a rare cognomen. The family name Hofhuis is characteristic of Netherlands, where it is quite a rare surname, Belgium, where it is a very rare surname, and South Africa. In absolute terms, it is the most numerous in Netherlands, South Africa, and Germany.
| VARIANT | COUNTRY |
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| Hofhuis | Netherlands, Belgium, Canada, Germany, South Africa |
| hendrika hofhuis executed for witchcraft, NL (b. 1780) |
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| joep hofhuis researcher |
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| hugo hofhuis researcher |
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| kevin hofhuis researcher (ORCID 0000-0002-1642-4786) |
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| agnetha hofhuis researcher |
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