Family name Hesse (Hesse 
, هسه 
, هيس , among others...) , around the globe, is a common last name. The last name Hesse is characteristic of Germany, where it is quite a common surname, Antigua and Barbuda, and Ghana, where it is quite a rare surname. Measured by absolute frequency, it is the most numerous in Germany, the United States, and Ghana. Very seldom, Hesse is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Hesse | France, Ghana, Australia, United States, Germany |
| هسه | Iraq, Egypt |
| هيس | Iraq |
| Гессе | Belarus, Kazakhstan, Russia, Ukraine |
| هيسه | Egypt, Palestinian Territory |
| הסן | Israel |
| henry the younger of hesse Landgrave of Hesse (b. 1264) |
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| herman de hesse Peerage person ID=532308, DE (b. 1301) |
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| benedykt hesse Polish religious scholar and philosopher, PL (b. 1389) |
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eoban hesse 16th-century German poet, DE (b. 1488) |
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| hans hesse German painter, DE (b. 1470) |
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| bartholomeus hesse (b. 1518) |
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| heinrich hesse DE (b. 1520) |
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| bartholomäus hesse (b. 1556) |
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| johann hesse DE (b. 1621) |
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| margaret van hesse (1635-1710) (b. 1635) |
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| johann kaspar hesse (b. 1627) |
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| heinrich wilhelm hesse DE (b. 1629) |
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| johann david hesse DE (b. 1639) |
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| andreas hesse (b. 1639) |
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ludwig wilhelm von hessen-homburg (1705-1745), DE (b. 1705) |
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