Cognomen Grigsby (Grigsby 
) , worldwide, is a common last name. The last name Grigsby is characteristic of Liberia, where it is quite a rare surname, the United States, and New Zealand, where it is a rare surname. In absolute terms, the name is most common in the United States, Liberia, and Canada.
| VARIANT | COUNTRY |
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| Grigsby | Canada, Liberia, Australia, United States, United Kingdom |
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melvin grigsby American attorney, politician, and military leader, US (b. 1845) |
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| hugh blair grigsby American historian, US (b. 1806) |
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| andrew j. grigsby American army officer, US (b. 1819) |
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sioux k. grigsby American lawyer and politician (1873-1968), US (b. 1873) |
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george barnes grigsby American politician, US (b. 1874) |
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| john warren grigsby (b. 1818) |
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emilie grigsby US (b. 1879) |
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| susan preston shelby grigsby (b. 1830) |
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denver grigsby Major League Baseball outfielder (1901-1973), US (b. 1901) |
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michael grigsby British filmmaker, GB (b. 1936) |
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| john t. grigsby American politician and lawyer (1890-1977), US (b. 1890) |
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| joan s. grigsby GB (b. 1891) |
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| william grigsby American photographer, US (b. 1915) |
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| eugene grigsby, jr. American painter, US (b. 1918) |
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| bill grigsby American football broadcaster, US (b. 1922) |
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