Surname Descartes (Descartes 
, ديكارت 
, דקארט 
) , worldwide, is quite a rare last name. The cognomen Descartes is characteristic of Saint Lucia, where it is quite a common surname, Belgium, where it is a rare surname, and Cameroon. Measured by absolute frequency, it most frequently occurs in France, Saint Lucia, and Cameroon. Also, Descartes is the forename as well as the last name.
| VARIANT | COUNTRY |
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| Descartes | Saint Lucia, France, Democratic Republic of the Congo, Cameroon, United States |
| ديكارت | Morocco |
| דקארט | Israel |
| gilles descartes French politician, FR (b. 1455) |
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joachim descartes French jurist (1563-1640), FR (b. 1563) |
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rené descartes French philosopher, mathematician, and scientist (1596-1650), FR (b. 1596) |
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francine descartes Rene Descartes' daughter, NL (b. 1635) |
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| pierre descartes (1591-1660), FR (b. 1591) |
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| catherine descartes French poet, FR (b. 1637) |
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| philippe descartes (b. 1640) |
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| sol luis descartes Puerto Rican politician (b. 1911) |
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| descartes marques gadelha Brazilian painter, BR (b. 1943) |
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| louis descartes (b. 1951) |
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| marat descartes Brazilian actor, BR (b. 1975) |
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| olivia descartes cyclist, LC |
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| maria descartes researcher |
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| sylvie descartes researcher |
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