Family name Defeo (Defeo 
) , all over the world, is quite a common cognomen. The family name Defeo is characteristic of Philippines, where it is quite a rare surname, Argentina, and the United States, where it is a rare surname.
| VARIANT | COUNTRY |
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| Defeo | Philippines, Italy, United States, United Kingdom, Argentina |
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ronald joseph defeo jr. American mass murderer (1951–2021), US (b. 1951) |
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| charles defeo US (b. 1892) |
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| peter defeo American mobster (1902-1993) (b. 1902) |
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| jay defeo American painter and photographer, US (b. 1929) |
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| omar defeo UY (b. 1920) |
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| carlos defeo Argentine actor, AR |
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| patrick anthony defeo Ph.D. Virginia Polytechnic Institute and State University 1988 |
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| omar defeo researcher |
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| carlos defeo actor |
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| luigi defeo IT |
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